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Applications The Future of VHH Research: Ongoing Innovations and Applications End of story? Probably not. Research on VHHs is thriving and new applications will surface every now and then. Visit this page from time to time to learn new applications of VHHs.
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Applications Innovative Drug Delivery: Enhancing Lipid Nanoparticles with VHHs for Targeted Therapy Lipid nanoparticles (LNPs) represent an exquisite and innovative means of transporting a cargo (drug) for controlled release during circulation in the body. A major concern for researchers and companies alike is to formulate the
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Applications Targeted Drug Delivery: Leveraging VHHs to Enhance Specificity and Reduce Side Effects Many small molecule drugs are known to cause side effects, stemming from their ability to non-specifically target healthy cells or tissue in addition to infected cells. Ideally, a drug only acts where it
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Applications Enhancing Food Safety: The Role of VHHs in Pathogen Detection The food chain is long and complex. Quality control along the chain at every stage is a must, since food for human consumption is usually also food for other organisms, including pathogens. VHHs can play
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Applications Utilizing VHHs for Plant Protection: Addressing Pathogen Threats and Enhancing Crop Resilience Numerous physiological processes in nature are mediated by proteins or polypeptides, in health and in disease. This not only applies to humans, but also to all kinds of micro-organisms, some of which known
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Applications Innovative Approaches to Combat Antibiotic Resistance: The Role of VHHs Antibiotic resistance is a major concern and this is likely to increase in the future, both in and outside of the clinic. While new ‘conventional’ antibiotics are being developed to tackle this threat, VHHs can
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Applications Harnessing VHHs in Gene Therapy: Expanding Therapeutic Reach in the Cytoplasm Due to their small size (~120 amino acids), the cDNA encoding a VHH is barely 0.35-0.4 kb. This makes them adaptable to gene therapy and indeed a VHH is easily accommodated within the genome
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Applications Enhancing CAR-T Cell Function with VHHs: Overcoming Exhaustion and Improving Targeting It is know that T-cells used in CAR-T at times become exhausted prematurely before performing their actual therapeutic role. This may be caused by VL and VH mispairing (originating from the scFvs), triggering premature
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Applications The Versatility of VHHs as Intrabodies for Cellular Applications The stability of VHHs as intrabodies in the cytoplasm of cells is one of their most advantageous properties. Indeed, it allows researchers to deploy VHHs as a multimodal tool. One can detect, block, perturb, degrade, image,
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Applications How Can We Help? Sed do eiusmod tempor incididunt ut labore dolore magna aliqua enim. Contact Us Enhancing Super-Resolution Microscopy with Direct Fluorescent Labeling of VHHs In typical staining experiments, the fluorophore is at some distance from the antigen. While this may not disturb conventional
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